SCHEMBL7130482

SCHEMBL7130482

CCO[Si](OCC)(OCC)C(CC)C(C(=O)N(CC)CC)C(=O)N(CC)CC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959216 0.77
SCHEMBL8813853 0.76 ALDH1A1 (0.36) LMNAALDH1A1HTT
SCHEMBL28334108 0.73
SCHEMBL7130493 0.70 ALDH1A1 (0.33) LMNAALDH1A1HTTSMN1; SMN2
SCHEMBL5809591 0.69
SCHEMBL27589740 0.65
SCHEMBL443030 0.64 MGAM (0.30)
SCHEMBL1584742 0.64 LMNA (0.35) LMNA
SCHEMBL17784252 0.63
SCHEMBL29039761 0.63 CA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6667016-B1 Contacting aqueous solution of ions with hybrid gel obtained by polycondensing, in solvent comprising water, at least one functionalized silicon alkoxide with metallic alkoxide, separating gel from aqueous solution COMMISSARIAT A L'ENERGIE ATOMIQUE AND COMPAGNIE GENERALE DES MATIERES NUCLEAIRES (FR) 2003-12-23 US disclosed