Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888156 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNANPSR1MAPTHPGD | |
| SCHEMBL8959216 | 0.82 | — | — | |
| SCHEMBL28334108 | 0.77 | — | — | |
| SCHEMBL7130482 | 0.76 | LMNA (0.32) | ALDH1A1LMNAHTT | |
| SCHEMBL8413238 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGDHSD17B10GAA | |
| SCHEMBL2460611 | 0.72 | ALDH1A1 (0.56) | ALDH1A1LMNANPSR1MAPTHPGD | |
| SCHEMBL443030 | 0.72 | MGAM (0.30) | GAAMGAMSIMGAM2 | |
| SCHEMBL23164135 | 0.70 | ALDH1A1 (0.42) | ALDH1A1LMNANPSR1MAPTHPGD | |
| Ethane SCHEMBL27513819 | 0.70 | ALDH1A1 (0.42) | ALDH1A1LMNANPSR1MAPTHPGD | |
| SCHEMBL7512461 | 0.69 | ALDH1A1 (0.46) | ALDH1A1LMNANPSR1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698309-A | OXIDE PARTICLES HAVE BEEEN SUBJECTED TO SURFACE MODIFICATION WITH SILYLATING AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
| US-5494949-A | SILANIZING INORGANIC OXIDES FOR COVALENT BONDING TO POLYESTER; FILLERS, REDUCTION OF VOIDS IN FILMS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-02-27 | — | — | US | disclosed |