Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138759 | 0.93 | PTGS2 (0.48) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7135328 | 0.85 | GCK (0.47) | KMT2ASMN1; SMN2FNTAFNTBLMNA | |
| SCHEMBL205699 | 0.78 | NPY5R (0.78) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7137876 | 0.76 | CCR4 (0.44) | MEN1KMT2AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7077860 | 0.75 | GABBR2 (0.49) | MAPTALDH1A1FNTAFNTBRAB9A | |
| SCHEMBL7077840 | 0.75 | GABBR2 (0.49) | MAPTALDH1A1FNTAFNTBRAB9A | |
| SCHEMBL12297209 | 0.72 | PTGS2 (0.67) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7132373 | 0.71 | SCN1A (0.46) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12297701 | 0.71 | PTGS2 (0.65) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL12297326 | 0.70 | PTGS2 (0.83) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |