SCHEMBL7130927

SCHEMBL7130927

Cn1c2c(c3ccccc31)C(C(C)(C)C1=CC(C34CC5CC(CC(C5)C3)C4)=CC1)c1ccccc1-2

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7117735 0.81 WDR5 (0.31)
SCHEMBL7130923 0.80 HSD11B1 (0.31) HSD11B1
Hydrochloric Acid SCHEMBL7128801 0.77 HSD11B1 (0.32) HSD11B1
SCHEMBL7124382 0.76 NTRK1 (0.33)
SCHEMBL7680001 0.75
Hydrochloric Acid SCHEMBL7168687 0.75 WDR5 (0.30)
SCHEMBL7127988 0.72 NTRK1 (0.40)
SCHEMBL7129142 0.70 NTRK1 (0.38)
Hydrochloric Acid SCHEMBL7128798 0.69 HSD11B1 (0.31) HSD11B1
SCHEMBL7129138 0.68 WDR5 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030148877-A1 Metallocenes and catalysts for olefin-polymerisation BASELL TECHNOLOGY COMPANY BV (NL) 2003-08-07 US disclosed
EP-0952978-B1 METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP disclosed
US-6451724-B1 BIS(N-METHYL-5,10-DIHYDROINDENO(1,2-B)INDOL-10 -YL)TITANIUM DICHLORIDE BASELL TECHNOLOGY COMPANY BV (NL) 2002-09-17 US disclosed
EP-0952978-A1 METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION Montell Technology Company bv (NL) 1999-11-03 EP disclosed
WO-1999024446-A1 METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION MONTELL TECHNOLOGY COMPANY B.V. (NL) 1999-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030148877-A1 Metallocenes and catalysts for olefin-polymerisation MT-CO1, CPNE4, MT-CO3 HSD11B1 2576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.