Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144925 | 0.80 | LMNA (0.39) | MAPTHTTLMNA | |
| SCHEMBL10797153 | 0.80 | LMNA (0.51) | ALDH1A1MAPTGAATAS1R3TAS1R1 | |
| SCHEMBL1144923 | 0.79 | LMNA (0.39) | LMNA | |
| SCHEMBL4585693 | 0.78 | POLB (0.37) | ALDH1A1MAPTGAATAS1R3TAS1R1 | |
| SCHEMBL10907187 | 0.78 | BACE1 (0.57) | ALDH1A1MAPTGAATSHR | |
| SCHEMBL27681020 | 0.77 | MAPT (0.42) | ALDH1A1MAPTPOLBLMNAKMT2A | |
| SCHEMBL10599484 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTGAATAS1R3TAS1R1 | |
| SCHEMBL28861359 | 0.76 | MAPT (0.41) | ALDH1A1MAPTPOLBLMNAKMT2A | |
| SCHEMBL7902799 | 0.76 | MAPT (0.53) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL10799202 | 0.75 | LMNA (0.40) | ALDH1A1GAATSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1166106-A4 | REAGENT AND METHOD FOR DETECTING AN ADULTERANT IN AN AQUEOUS SAMPLE | QUEST DIAGNOSTICS INVEST INC (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1166106-A1 | REAGENT AND METHOD FOR DETECTING AN ADULTERANT IN AN AQUEOUS SAMPLE | Quest Diagnostics Investments Incorporated (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000052464-A1 | REAGENT AND METHOD FOR DETECTING AN ADULTERANT IN AN AQUEOUS SAMPLE | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) | 2000-09-08 | — | — | WO | disclosed |