Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132181 | 0.78 | ALDH1A1 (0.39) | POLBMEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL5578301 | 0.71 | NR3C1 (0.35) | MEN1KMT2AMAPTUSP2LMNA | |
| SCHEMBL8679853 | 0.71 | ADRA2B (0.53) | POLBMEN1KMT2AG6PDAR | |
| SCHEMBL8283681 | 0.70 | MEN1 (0.43) | POLBMEN1KMT2AG6PDAR | |
| SCHEMBL4252040 | 0.69 | AR (0.49) | POLBMEN1KMT2AG6PDAR | |
| SCHEMBL29462975 | 0.69 | AR (0.49) | POLBMEN1KMT2AG6PDAR | |
| SCHEMBL9485850 | 0.69 | NQO2 (0.56) | POLBMEN1KMT2AG6PDAR | |
| SCHEMBL10343496 | 0.68 | AR (0.44) | POLBMEN1KMT2AG6PDAR | |
| SCHEMBL6049289 | 0.68 | ADRB3 (0.47) | POLBKMT2AARL3MBTL1ALDH1A1 | |
| SCHEMBL22868422 | 0.68 | POLB (0.50) | POLBMEN1KMT2AG6PDAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805322-A4 | ENZYME CYCLING BASED ASSAYS FOR ALPHA-METHYLACYL-CoA RACEMASE | GEN ATOMICS (US) | 2008-10-08 | — | — | EP | disclosed |
| US-7374897-B2 | Enzyme cycling based assays for alpha-methylacyl-CoA racemase | GENERAL ATOMICS (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1805322-A1 | ENZYME CYCLING BASED ASSAYS FOR ALPHA-METHYLACYL-CoA RACEMASE | GENERAL ATOMICS (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006044633-A1 | ENZYME CYCLING BASED ASSAYS FOR ALPHA-METHYLACYL-CoA RACEMASE | GENERAL ATOMICS (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060084132-A1 | Enzyme cycling based assays for alpha-methylacyl-CoA racemase | GENERAL ATOMICS | 2006-04-20 | — | — | US | disclosed |