SCHEMBL7132995

SCHEMBL7132995

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nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.61
LMNA P02545 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.48
USP2 O75604 1/20 0.47
SLCO1B1 Q9Y6L6 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
KDM4E B2RXH2 2/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
OR51E2 Q9H255 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28066668 1.00 PDE4A (0.61) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL378867 1.00 PDE4A (0.61) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL6234202 0.98 PDE4A (0.59) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL9576619 0.98 PDE4A (0.59) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL15453928 0.93 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL1129690 0.93 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL8218436 0.93 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL14124935 0.84 PDE4A (0.44) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL27216229 0.84 PDE4A (0.44) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL1635580 0.83 LMNA (0.59) PDE4ALMNAL3MBTL1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6503885-B1 Selectin inhibitors; anticarcinogenic, antiinflammatory, and antimetastasis agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-01-07 US claimed
US-12187817-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues KODE BIOTECH LIMITED (NZ) 2025-01-07 US disclosed
US-20230374076-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES KODE BIOTECH LIMITED (NZ) 2023-11-23 US disclosed
US-11760779-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues KODE BIOTECH LIMITED (NZ) 2023-09-19 US disclosed
US-20210214396-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES KODE BIOTECH LIMITED (NZ) 2021-07-15 US disclosed
WO-2018220603-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES BOVIN NICOLAI VLADIMIROVICH (RU) 2018-12-06 WO disclosed
US-6503885-B1 Selectin inhibitors; anticarcinogenic, antiinflammatory, and antimetastasis agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-01-07 US disclosed
US-6503885-B1 Selectin inhibitors; anticarcinogenic, antiinflammatory, and antimetastasis agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-01-07 US disclosed
US-6503885-B1 Selectin inhibitors; anticarcinogenic, antiinflammatory, and antimetastasis agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-01-07 US disclosed
WO-2000017216-A1 CARBOXYMETHYLGALACTOSE DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2000-03-30 WO disclosed
EP-0929562-A1 ACID-FUNCTIONALIZED SACCHARIDES AS POLYVALENT ANTI-INFECTIVES GELTEX PHARMACEUTICALS, INC. (US) 1999-07-21 EP disclosed
US-5821312-A Acid-functionalized saccharides as polyvalent anti-infectives GELTEX PHARMACEUTICALS, INC. (US) 1998-10-13 US disclosed
WO-1998012203-A1 ACID-FUNCTIONALIZED SACCHARIDES AS POLYVALENT ANTI-INFECTIVES GELTEX PHARMACEUTICALS, INC. (US) 1998-03-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230374076-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES SGMS1, SGMS2, CERT1 PDE4A 3915/4885LMNA 76/4885L3MBTL1 1439/4885
US-11760779-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues SGMS1, SGMS2, CERT1 PDE4A 3784/4885LMNA 107/4885L3MBTL1 1635/4885
US-20210214396-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES SGMS1, SGMS2, CERT1 PDE4A 3955/4885LMNA 77/4885L3MBTL1 1405/4885
US-12187817-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues SGMS1, SGMS2, CERT1 PDE4A 3770/4885LMNA 113/4885L3MBTL1 1662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.