SCHEMBL378867

SCHEMBL378867

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nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.61
LMNA P02545 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.48
USP2 O75604 1/20 0.47
SLCO1B1 Q9Y6L6 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
KDM4E B2RXH2 2/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
OR51E2 Q9H255 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7132995 1.00 PDE4A (0.61) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL28066668 1.00 PDE4A (0.61) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL6234202 0.98 PDE4A (0.59) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL9576619 0.98 PDE4A (0.59) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL15453928 0.93 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL1129690 0.93 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL8218436 0.93 PDE4A (0.52) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL14124935 0.84 PDE4A (0.44) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL27216229 0.84 PDE4A (0.44) PDE4ALMNAL3MBTL1USP2SLCO1B1
SCHEMBL1635580 0.83 LMNA (0.59) PDE4ALMNAL3MBTL1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116139336-B Multichannel biological scaffold and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2024-09-10 CN claimed
CN-113893219-B Drug-loaded nano micelle, preparation method, application and method for preparing planting base station based on drug-loaded nano micelle 中国人民解放军空军军医大学 2023-06-23 CN claimed
US-20230191003-A1 COMPOSITE SCAFFOLD MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Suzhou Novovita Bio-products Co., Ltd. (CN) 2023-06-22 US claimed
CN-116139336-A Multichannel biological scaffold and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2023-05-23 CN claimed
US-20230118503-A1 NEUTRAL ENDOPEPTIDASE (NEP) AND HUMAN SOLUBLE ENDOPEPTIDASE (hSEP) INHIBITORS FOR PROPHYLAXIS AND TREATMENT OF EYE DISEASES TURSKI CHRISTOPHER (US) 2023-04-20 US claimed
US-20230095764-A1 NOVEL KETOGENIC COMPOUNDS, COMPOSITIONS, METHODS AND USE THEREOF KETOFIBE (9211-3133 QUEBEC INC.) (CA) 2023-03-30 US claimed
CN-115120562-A Drug-loaded nanofiber scaffold particle and preparation method and application thereof 苏州博创同康生物工程有限公司 2022-09-30 CN claimed
CN-113893219-A Drug-loaded nano micelle, preparation method thereof, application of drug-loaded nano micelle in preparation of implant abutment and method for preparing implant abutment based on drug-loaded nano micelle 中国人民解放军空军军医大学 2022-01-07 CN claimed
US-20210275475-A1 NOVEL KETOGENIC COMPOUNDS, COMPOSITIONS, METHODS AND USE THEREOF 9500-0535 QUEBEC INC. (CA) 2021-09-09 US claimed
EP-3806906-A1 NOVEL KETOGENIC COMPOUNDS, COMPOSITIONS, METHODS AND USE THEREOF Ketofibe (9211-3133 Quebec Inc.) (CA) 2021-04-21 EP claimed
CN-103432087-B Clindamycin hydrochloride preparation for injection and preparation method thereof WUHAN PUSHENG PHARMACEUTICAL CO LTD 2015-02-18 CN claimed
CN-104103820-A Spherical porous channel graphite negative electrode material of lithium ion battery and preparation method thereof PETER WAN 2014-10-15 CN claimed
CN-103880138-A High-efficiency flocculating agent for waste water treatment SHANGHAI HESHUN CHEMICAL TECHNOLOGY CO LTD 2014-06-25 CN claimed
CN-103432087-A Clindamycin hydrochloride preparation for injection and preparation method thereof WUHAN PUSHENG PHARMACEUTICAL CO LTD 2013-12-11 CN claimed
CN-103417514-A Microencapsulated butylphthalide medicine composition, preparation method and applications CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY SHIJIAZHUANG CO LTD 2013-12-04 CN claimed
CN-102709566-A Spherical silicon carbon composite anode material of lithium ion battery and preparation method for spherical silicon carbon composite anode material LIXIN QINGDAO NEW ENERGY MATERIALS CO LTD 2012-10-03 CN claimed
US-20100009007-A1 Non-covalent modification of microparticles and process of preparing same BAXTER INTERNATIONAL INC. (US) 2010-01-14 US claimed
WO-2010006194-A2 NON-COVALENT MODIFICATION OF MICROPARTICLES AND PROCESS OF PREPARING SAME BAXTER INTERNATIONAL INC. (US) 2010-01-14 WO claimed
CN-1692910-A Oral prepn. of disodium adenosine triphosphate SUN MINGJIE (CN) 2005-11-09 CN claimed
US-4649050-A Electrolyte solutions containing polyanionic materials BRITISH TECHNOLOGY GROUP LIMITED (GB) 1987-03-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230095764-A1 NOVEL KETOGENIC COMPOUNDS, COMPOSITIONS, METHODS AND USE THEREOF PC, LRBA, BCKDK PDE4A 2451/4885LMNA 2310/4885L3MBTL1 1517/4885
US-20100009007-A1 Non-covalent modification of microparticles and process of preparing same CHMP4B, PHOSPHO1, PLTP PDE4A 2106/4885LMNA 1772/4885L3MBTL1 3882/4885
US-20230118503-A1 NEUTRAL ENDOPEPTIDASE (NEP) AND HUMAN SOLUBLE ENDOPEPTIDASE (hSEP) INHIBITORS FOR PROPHYLAXIS AND TREATMENT OF EYE DISEASES MME, ECE1, ENPEP PDE4A 871/4885LMNA 535/4885L3MBTL1 4720/4885
US-20210275475-A1 NOVEL KETOGENIC COMPOUNDS, COMPOSITIONS, METHODS AND USE THEREOF PC, LRBA, GPR119 PDE4A 2464/4885LMNA 2248/4885L3MBTL1 1690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.