Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.85 |
| ▸ | MMP9 | P14780 | 16/20 | 0.85 |
| ▸ | MMP13 | P45452 | 16/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929195 | 0.92 | MMP13 (1.00) | MMP1MMP9MMP13 | |
| SCHEMBL6928992 | 0.89 | MMP1 (1.00) | MMP1MMP9MMP13 | |
| Diethylamine SCHEMBL6933694 | 0.84 | MMP13 (0.74) | MMP1MMP9MMP13 | |
| SCHEMBL7133713 | 0.84 | MMP1 (0.68) | MMP1MMP9MMP13 | |
| SCHEMBL6928993 | 0.83 | MMP1 (0.69) | MMP1MMP9MMP13 | |
| SCHEMBL6933162 | 0.83 | MMP13 (0.71) | MMP1MMP9MMP13 | |
| SCHEMBL6930709 | 0.82 | MMP13 (1.00) | MMP1MMP9MMP13 | |
| SCHEMBL7072896 | 0.81 | MMP9 (0.74) | MMP1MMP9MMP13 | |
| SCHEMBL7071270 | 0.81 | MMP13 (0.80) | MMP1MMP9MMP13 | |
| Diethylamine SCHEMBL6932200 | 0.81 | MMP13 (0.71) | MMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970046-B1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH CORP (US) | 2003-12-10 | — | — | EP | disclosed |
| US-6444704-B1 | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, ANTITUMOR AGENTS | AMERICAN HOME PRODUCTS CORPORATION | 2002-09-03 | — | — | US | disclosed |
| US-6342508-B1 | ENZYME INHIBITORS FOR PROTECTION OF CONNECTIVE TISSUES | AMERICAN CYANAMID COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-6172057-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY | 2001-01-09 | — | — | US | disclosed |