SCHEMBL7784378

SCHEMBL7784378

O=CCCCCCCCOCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 1/20 0.48
EPHX2 P34913 2/20 0.44
TEAD3 Q99594 1/20 0.43
HRH4 Q9H3N8 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
GBA1 P04062 2/20 0.41
UGCG Q16739 2/20 0.41
GBA2 Q9HCG7 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NAAA Q02083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6211503 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHREPHX2TEAD3
SCHEMBL1009942 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHREPHX2TEAD3
SCHEMBL9875114 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHREPHX2TEAD3
SCHEMBL27274855 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHREPHX2TEAD3
SCHEMBL711369 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHREPHX2TEAD3
SCHEMBL18585071 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHREPHX2TEAD3
SCHEMBL5561948 1.00 L3MBTL1 (0.50) L3MBTL1TDP1TSHREPHX2TEAD3
SCHEMBL713499 0.98 TSHR (0.50) L3MBTL1TDP1TSHREPHX2TEAD3
SCHEMBL6263416 0.93 TSHR (0.52) L3MBTL1TDP1TSHREPHX2TEAD3
SCHEMBL710282 0.93 TSHR (0.52) L3MBTL1TDP1TSHREPHX2TEAD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739652-A1 LIPIDS AND COMPOSITIONS THEREOF Kernal Biologics, Inc. (US) 2026-05-13 EP disclosed
US-20260116845-A1 LIPIDS AND COMPOSITIONS THEREOF KERNAL BIOLOGICS INC (US) 2026-04-30 US disclosed
WO-2025134071-A1 MALIC AND GLUTARIC ACID BASED IONIZABLE LIPIDS SANOFI (FR) 2025-06-26 WO disclosed
WO-2025010290-A1 LIPIDS AND COMPOSITIONS THEREOF KERNAL BIOLOGICS, INC. (US) 2025-01-09 WO disclosed
US-20230338552-A1 LIPID PRODRUGS OF NEUROSTEROIDS PURETECH LYT, INC. (US) 2023-10-26 US disclosed
US-20230338552-A1 LIPID PRODRUGS OF NEUROSTEROIDS PURETECH LYT, INC. (US) 2023-10-26 US disclosed
WO-2023147545-A2 PROCESS FOR PD(II)-CATALYZED SITE-SELECTIVE BETA- AND GAMMA-C(SP3)-H ARYLATION OF PRIMARY ALDEHYDES CONTROLLED BY TRANSIENT DIRECTING GROUPS THE SCRIPPS RESEARCH INSTITUTE (US) 2023-08-03 WO disclosed
US-20220395513-A1 LIPID PRODRUGS OF NEUROSTEROIDS PURETECH LYT, INC. (US) 2022-12-15 US disclosed
US-20220125933-A1 LIPID PRODRUGS OF JAK INHIBITORS AND USES THEREOF SEAPORT THERAPEUTICS, INC. 2022-04-28 US disclosed
US-20210300962-A1 LIPID PRODRUGS OF PREGNANE NEUROSTEROIDS AND USES THEREOF SEAPORT THERAPEUTICS, INC. 2021-09-30 US disclosed
WO-2021159021-A1 LIPID PRODRUGS OF NEUROSTEROIDS PURETECH LYT, INC. (US) 2021-08-12 WO disclosed
EP-1141172-A1 LIQUID CRYSTAL MATERIALS QinetiQ Limited (GB) 2001-10-10 EP disclosed
WO-2000029505-A1 LIQUID CRYSTAL MATERIALS THE SECRETARY OF STATE FOR DEFENCE (GB) 2000-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338552-A1 LIPID PRODRUGS OF NEUROSTEROIDS CYP21A2, CYP46A1, CYP17A1 L3MBTL1 3485/4885TDP1 1452/4885TSHR 1372/4885
US-20220125933-A1 LIPID PRODRUGS OF JAK INHIBITORS AND USES THEREOF JAK1, JAK2, JAK3 L3MBTL1 1375/4885TDP1 1941/4885TSHR 2195/4885
US-20210300962-A1 LIPID PRODRUGS OF PREGNANE NEUROSTEROIDS AND USES THEREOF CYP21A2, CYP46A1, CYP17A1 L3MBTL1 3700/4885TDP1 1706/4885TSHR 1457/4885
US-20220395513-A1 LIPID PRODRUGS OF NEUROSTEROIDS CYP21A2, CYP46A1, CYP17A1 L3MBTL1 3485/4885TDP1 1452/4885TSHR 1372/4885
US-20260116845-A1 LIPIDS AND COMPOSITIONS THEREOF LIPC, LIPA, NPC1L1 L3MBTL1 295/4885TDP1 1579/4885TSHR 1603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.