Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263416 | 1.00 | TSHR (0.52) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL20305579 | 0.96 | TSHR (0.48) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL713499 | 0.94 | TSHR (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL9875114 | 0.93 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL18585071 | 0.93 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL5561948 | 0.93 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL711369 | 0.93 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL6211503 | 0.93 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL1009942 | 0.93 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 | |
| SCHEMBL7784378 | 0.93 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1TEAD3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145368-B2 | Organocatalytic synthesis of chiral pyrazolidines and their analogues | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-09-29 | — | — | US | claimed |
| US-20140357872-A1 | NEW ORGANOCATALYTIC SYNTHESIS OF CHIRAL PYRAZOLIDINES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-04 | — | — | US | claimed |
| WO-2013088456-A1 | A NEW ORGANOCATALYTIC SYNTHESIS OF CHIRAL PYRAZOLIDINES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-06-20 | — | — | WO | claimed |
| EP-1001943-B1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-12-17 | — | — | EP | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| JP-58152829-A | — | — | None | — | — | JP | disclosed |
| EP-4142732-B1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4720058-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | Casma Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4712948-A2 | GENE EDITING SYSTEMS AND COMPOSITIONS FOR TREATMENT OF HEMOGLOBINOPATHIES AND METHODS OF USING THE SAME | Renagade Therapeutics Management Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20250282795-A1 | EGFR Inhibitors in cancer treatment | CELYN THERAPEUTICS, INC. | 2025-09-11 | — | — | US | disclosed |
| US-20250170248-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-05-29 | — | — | US | disclosed |
| WO-1995022330-A1 | ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-08-24 | — | — | WO | disclosed |
| WO-1995021815-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND SQUALENE SYNTHASE | ABBOTT LABORATORIES (US) | 1995-08-17 | — | — | WO | disclosed |
| EP-0420806-B1 | Phosphonic acids, process for preparation and use as an active pharmaceutical composition | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| US-5294734-A | 1-phosphato-4-amino-pent-2-enoic acids and derivatives | CIBA-GEIGY CORP. (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0420806-A1 | Phosphonic acids, process for preparation and use as an active pharmaceutical composition | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |
| JP-S58152829-A | 1,2,3,7,8,8A-HEXAHYDRO-1-HYDROXY-7-METHYL-8-(3'-HYDROXY) PROPYLNAPHTHALENE | SUNTORY LTD | 1983-09-10 | — | — | JP | disclosed |
| US-4131623-A | FROM DIHYDRO-1,3-OXAZINES, DECYCLIZATION | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL & MECHANICAL COLLEGE (US) | 1978-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250170248-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCA2, SMARCC2 | TSHR 4388/4885L3MBTL1 2934/4885TDP1 151/4885 |
| US-20250282795-A1 | EGFR Inhibitors in cancer treatment | EGFR, ERBB2, ERBB4 | TSHR 1283/4885L3MBTL1 4099/4885TDP1 3957/4885 |
| US-20140357872-A1 | NEW ORGANOCATALYTIC SYNTHESIS OF CHIRAL PYRAZOLIDINES AND THEIR ANALOGUES | PDK2, PDXK, TALDO1 | TSHR 2344/4885L3MBTL1 3177/4885TDP1 2876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.