Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.63 |
| ▸ | BMP1 | P13497 | 1/20 | 0.62 |
| ▸ | BRS3 | P32247 | 4/20 | 0.61 |
| ▸ | NMBR | P28336 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135018 | 1.00 | MMP1 (0.63) | MMP1BMP1BRS3NMBRMEN1 | |
| SCHEMBL1233776 | 0.94 | BMP1 (0.68) | MMP1BMP1BRS3NMBR | |
| SCHEMBL7257081 | 0.89 | NMBR (0.64) | BMP1BRS3NMBR | |
| SCHEMBL7252292 | 0.89 | BRS3 (0.64) | BMP1BRS3NMBR | |
| SCHEMBL7256825 | 0.88 | BMP1 (0.63) | BMP1BRS3NMBR | |
| SCHEMBL7255942 | 0.88 | BRS3 (0.65) | BMP1BRS3NMBRKMT2A | |
| Hydrochloric Acid SCHEMBL7251808 | 0.87 | BMP1 (0.62) | BMP1BRS3NMBR | |
| SCHEMBL1233724 | 0.87 | HDAC3 (0.67) | MMP1BMP1NMBRMEN1HCRTR1 | |
| SCHEMBL7138854 | 0.87 | HDAC3 (0.67) | MMP1BMP1NMBRMEN1HCRTR1 | |
| SCHEMBL1233735 | 0.86 | BMP1 (0.63) | MMP1BMP1BRS3NMBRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335898-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | Prolifix Limited (GB) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002026696-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | PROLIFIX LIMITED (GB) | 2002-04-04 | — | — | WO | disclosed |