SCHEMBL7252292

SCHEMBL7252292

NCCC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCCCc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRS3 P32247 6/20 0.64
NMBR P28336 5/20 0.63
BMP1 P13497 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7255942 0.97 BRS3 (0.65) BRS3NMBRBMP1
SCHEMBL7257081 0.96 NMBR (0.64) BRS3NMBRBMP1
SCHEMBL7256825 0.93 BMP1 (0.63) BRS3NMBRBMP1
SCHEMBL7253751 0.93 BRS3 (0.72) BRS3NMBR
Hydrochloric Acid SCHEMBL7251808 0.93 BMP1 (0.62) BRS3NMBRBMP1
SCHEMBL7135018 0.89 MMP1 (0.63) BRS3NMBRBMP1
SCHEMBL7135014 0.89 MMP1 (0.63) BRS3NMBRBMP1
SCHEMBL7256838 0.88 NMBR (0.71) BRS3NMBR
SCHEMBL1233776 0.88 BMP1 (0.68) BRS3NMBRBMP1
SCHEMBL7250838 0.87 TRPV1 (0.61) BRS3NMBRBMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030195212-A1 Novel melanocortin receptor agonists and antagonists MELACURE THERAPEUTICS AB (SE) 2003-10-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195212-A1 Novel melanocortin receptor agonists and antagonists MC1R, MC5R, MC4R BRS3 160/4885NMBR 264/4885BMP1 1781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.