Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229391 | 0.85 | ACLY (0.46) | MAPK1HTTKMT2AALDH1A1KDM4E | |
| SCHEMBL9836471 | 0.85 | MAPK1 (0.61) | MAPK1HTTKMT2AALDH1A1KDM4E | |
| SCHEMBL879030 | 0.83 | MAPK1 (0.64) | MAPK1HTTKMT2AALDH1A1KDM4E | |
| SCHEMBL20310394 | 0.83 | MAPK1 (0.59) | MAPK1HTTKMT2AALDH1A1KDM4E | |
| SCHEMBL2090906 | 0.82 | RAB9A (0.63) | HTTKMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL14053110 | 0.82 | ALDH1A1 (0.47) | MAPK1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL24252964 | 0.81 | MAPT (0.66) | MAPK1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL21949446 | 0.80 | MAPK1 (0.56) | MAPK1HTTKMT2AALDH1A1KDM4E | |
| SCHEMBL4261842 | 0.80 | MAPK1 (0.56) | MAPK1HTTKMT2AALDH1A1KDM4E | |
| SCHEMBL30930866 | 0.80 | MAPK1 (0.69) | MAPK1HTTKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015011252-A1 | PYRIMIDINE-PYRIDINONE SERINE/THREONINE KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-01-29 | — | — | WO | disclosed |
| CN-1520298-A | Pyrazolopyrimidines as therapeutic agents | �����ʩ���عɷݹ�˾ | 2004-08-11 | — | — | CN | disclosed |
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |
| CN-1390219-A | Pyrazolopyrimidines as therapeutic agents | ABBOTT AG (DE) | 2003-01-08 | — | — | CN | disclosed |