Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CCNC | P24863 | 2/20 | 0.44 |
| ▸ | CDK8 | P49336 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135266 | 1.00 | TTR (0.45) | TTRDPP4ALBCA12CA1 | |
| SCHEMBL6364609 | 0.85 | ALB (0.47) | TTRALBCA12CA1CA2 | |
| SCHEMBL6364611 | 0.85 | ALB (0.47) | TTRALBCA12CA1CA2 | |
| SCHEMBL12355545 | 0.82 | MEN1 (0.48) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL3204531 | 0.81 | ALB (0.49) | ALBNPC1RAB9AMCL1GRIN2D | |
| SCHEMBL3204520 | 0.81 | ALB (0.49) | ALBNPC1RAB9AMCL1GRIN2D | |
| SCHEMBL6364102 | 0.81 | LMNA (0.45) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL6364105 | 0.81 | LMNA (0.45) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL29247884 | 0.80 | GRIN2D (0.51) | ALBNPC1RAB9AMCL1GRIN2D | |
| SCHEMBL7326486 | 0.80 | MCL1 (0.54) | ALBNPC1RAB9AMCL1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |
| EP-0392663-A1 | Carboline derivative as a 5-HT3 receptor antagonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-10-17 | — | — | EP | disclosed |