Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364609 | 1.00 | ALB (0.47) | ALBKMT2AKDM4ESMN1; SMN2MCL1 | |
| SCHEMBL3204531 | 0.85 | ALB (0.49) | ALBKMT2AMCL1GRIN2DGRIN3B | |
| SCHEMBL3204520 | 0.85 | ALB (0.49) | ALBKMT2AMCL1GRIN2DGRIN3B | |
| SCHEMBL7135266 | 0.85 | TTR (0.45) | ALBKMT2AKDM4ESMN1; SMN2MCL1 | |
| SCHEMBL7135262 | 0.85 | TTR (0.45) | ALBKMT2AKDM4ESMN1; SMN2MCL1 | |
| SCHEMBL29247884 | 0.83 | GRIN2D (0.51) | ALBKMT2AKDM4ESMN1; SMN2MCL1 | |
| SCHEMBL7326492 | 0.83 | MCL1 (0.54) | ALBKMT2AMCL1GRIN2DGRIN3B | |
| SCHEMBL7326486 | 0.83 | MCL1 (0.54) | ALBKMT2AMCL1GRIN2DGRIN3B | |
| SCHEMBL9550204 | 0.83 | KDM4E (0.45) | KMT2AKDM4ESMN1; SMN2MCL1MEN1 | |
| SCHEMBL16756075 | 0.79 | RAB9A (0.51) | ALBKMT2AKDM4ESMN1; SMN2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070591-A1 | Indole derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-03-31 | — | — | US | disclosed |
| EP-1464645-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070591-A1 | Indole derivative | TPH1, IDO1, RBX1 | ALB 1442/4885KMT2A 1221/4885KDM4E 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.