Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713576 | 1.00 | MMP2 (0.46) | MMP2MMP9MMP8MMP13CETP | |
| SCHEMBL29015898 | 0.67 | MMP2 (0.44) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL712649 | 0.64 | MMP2 (0.44) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL14778371 | 0.62 | MMP2 (0.48) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL18344443 | 0.62 | MMP9 (0.88) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL20394107 | 0.62 | MMP9 (0.51) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL14778363 | 0.61 | MMP2 (0.50) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL14779509 | 0.61 | MMP2 (0.50) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL14779275 | 0.61 | MMP2 (0.50) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL14778333 | 0.61 | MMP2 (0.50) | MMP2MMP9MMP8MMP13MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124794-B2 | Method for the asymmetric synthesis of beta-lactone compounds | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | FASN, COASY, FADS1 | MMP2 1131/4885MMP9 1562/4885MMP8 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.