Cymopol

Cymopol

SCHEMBL29378158

CC(C)=CCC/C(C)=C/Cc1cc(O)c(Br)cc1O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.52
PTPN1 P18031 1/20 0.52
MAOB P27338 5/20 0.50
OSBP P22059 1/20 0.50
PPARG P37231 6/20 0.49
PPARA Q07869 5/20 0.49
APP P05067 2/20 0.49
PTGES O14684 1/20 0.47
ALOX5 P09917 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
TRPA1 O75762 1/20 0.46
INHA P05111 1/20 0.46
CNR1 P21554 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2A P28223 1/20 0.46
SLC6A4 P31645 1/20 0.46
CNR2 P34972 1/20 0.46
OPRM1 P35372 1/20 0.46
SLC6A3 Q01959 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cymopol SCHEMBL21055681 1.00 BACE1 (0.52) BACE1PTPN1MAOBOSBPPPARG
Cymopol SCHEMBL8649278 1.00 BACE1 (0.52) BACE1PTPN1MAOBOSBPPPARG
SCHEMBL9714237 0.91 PTPN1 (0.61) BACE1PTPN1MAOBOSBPPPARG
SCHEMBL9714250 0.91 PTPN1 (0.61) BACE1PTPN1MAOBOSBPPPARG
SCHEMBL7135772 0.83 BACE1 (0.57) BACE1PTPN1MAOBOSBPPPARG
SCHEMBL7080850 0.82 MAOB (0.63) BACE1PTPN1MAOBOSBPPPARG
SCHEMBL7048803 0.82 MAOB (0.63) BACE1PTPN1MAOBOSBPPPARG
SCHEMBL5820932 0.78 APP (0.52) BACE1PTPN1MAOBOSBPPPARG
SCHEMBL21055687 0.77 CYP1A1 (0.58) BACE1PTPN1OSBP
SCHEMBL21055680 0.77 CYP1A1 (0.58) BACE1PTPN1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226211-A9 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-07-11 US claimed
US-20240131097-A1 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-04-25 US claimed
US-12102653-B2 Ligand regulated protein-protein interaction system ST. ANNA KINDERKREBSFORSCHUNG (AT) 2024-10-01 US disclosed
US-20240226211-A9 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-07-11 US disclosed
US-20240131097-A1 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-04-25 US disclosed
US-20240000841-A1 LIGAND REGULATED PROTEIN-PROTEIN INTERACTION SYSTEM ST ANNA KINDERKREBSFORSCHUNG (AT) 2024-01-04 US disclosed
US-11844813-B2 Ligand regulated protein-protein interaction system ST. ANNA KINDERKREBSFORSCHUNG (AT) 2023-12-19 US disclosed
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) ST. ANNA KINDERKREBSFORSCHUNG (AT) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240131097-A1 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT KEAP1, NFE2L2, TFEB BACE1 133/4885PTPN1 4535/4885MAOB 3470/4885
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) CARS1, CD74, HAVCR2 BACE1 3128/4885PTPN1 1563/4885MAOB 4846/4885
US-20240226211-A9 SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT KEAP1, NFE2L2, TFEB BACE1 133/4885PTPN1 4535/4885MAOB 3470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.