Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 5/20 | 0.58 |
| ▸ | OSBP | P22059 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | PPARA | Q07869 | 4/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | INHA | P05111 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714250 | 1.00 | PTPN1 (0.61) | PTPN1BACE1MAOBOSBPAPP | |
| SCHEMBL7135772 | 0.92 | BACE1 (0.57) | PTPN1BACE1MAOBOSBPAPP | |
| SCHEMBL7080850 | 0.91 | MAOB (0.63) | PTPN1BACE1MAOBOSBPAPP | |
| Cymopol SCHEMBL21055681 | 0.91 | BACE1 (0.52) | PTPN1BACE1MAOBOSBPAPP | |
| Cymopol SCHEMBL8649278 | 0.91 | BACE1 (0.52) | PTPN1BACE1MAOBOSBPAPP | |
| SCHEMBL7048803 | 0.91 | MAOB (0.63) | PTPN1BACE1MAOBOSBPAPP | |
| Cymopol SCHEMBL29378158 | 0.91 | BACE1 (0.52) | PTPN1BACE1MAOBOSBPAPP | |
| SCHEMBL5820932 | 0.86 | APP (0.52) | PTPN1BACE1MAOBOSBPAPP | |
| SCHEMBL23896921 | 0.85 | MAOB (0.57) | PTPN1BACE1MAOBOSBPAPP | |
| Geroquinol SCHEMBL557012 | 0.85 | ALOX5 (0.57) | PTPN1BACE1MAOBOSBPAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341664-B1 | SKIN DEPIGMENTAL AGENT | KURARAY CO., LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |