Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133184 | 0.90 | KDM1A (0.52) | ERBB2KDM1AKMT2AALDH1A1MAPT | |
| SCHEMBL7132141 | 0.89 | KMT2A (0.53) | ERBB2KDM1AKMT2AALDH1A1MAPT | |
| SCHEMBL7133808 | 0.87 | DYRK1A (0.37) | KMT2AALDH1A1MAPTRET | |
| SCHEMBL7137722 | 0.87 | KDM1A (0.54) | TUBB1KDM1AKMT2AALDH1A1MAPT | |
| SCHEMBL7135307 | 0.86 | ERBB2 (0.57) | ERBB2KDM1AKMT2AALDH1A1MAPT | |
| SCHEMBL7138252 | 0.84 | ERBB2 (0.45) | ERBB2TUBB1KDM1AKMT2AALDH1A1 | |
| SCHEMBL7138706 | 0.84 | IGF1R (0.53) | KDM1AKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL7138260 | 0.82 | METAP1 (0.55) | KDM1AKMT2AMEN1PIM1PIM2 | |
| SCHEMBL7135160 | 0.82 | METAP1 (0.50) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| SCHEMBL7137199 | 0.81 | MEN1 (0.58) | KDM1AKMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506763-B2 | Useful in prevention and treatment of protein kinase related disorders such as cancer | SUGEN, INC. | 2003-01-14 | — | — | US | disclosed |