Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 18/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138977 | 0.88 | PARP1 (0.50) | PARP1DHODH | |
| SCHEMBL7137103 | 0.86 | PARP1 (0.55) | PARP1PIM1PIM3AURKB | |
| SCHEMBL7141044 | 0.86 | PARP1 (0.48) | PARP1PIM1PIM3AURKBMMP2 | |
| SCHEMBL7140624 | 0.85 | PARP1 (0.48) | PARP1PIM1PIM3AURKB | |
| SCHEMBL7139317 | 0.85 | PARP1 (0.58) | PARP1PIM1PIM3AURKBDHODH | |
| SCHEMBL7132446 | 0.84 | PARP1 (0.59) | PARP1PIM1PIM3AURKBDHODH | |
| SCHEMBL3585144 | 0.81 | PARP1 (0.64) | PARP1PIM1AURKBDHODH | |
| SCHEMBL7136544 | 0.81 | PARP1 (0.78) | PARP1PIM1PIM3AURKBDHODH | |
| SCHEMBL3579908 | 0.81 | PARP1 (0.61) | PARP1PIM1PIM3AURKBDHODH | |
| SCHEMBL3580302 | 0.81 | DYRK3 (0.54) | PARP1PIM1PIM3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509365-B1 | 2-phenylbenzimidazoles and 2-phenylindoles, and production and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-21 | — | — | US | disclosed |