Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 17/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136552 | 0.86 | PARP1 (0.52) | PARP1PIM1PIM3AURKBMMP2 | |
| SCHEMBL7137103 | 0.85 | PARP1 (0.55) | PARP1PIM1PIM3AURKB | |
| SCHEMBL7140624 | 0.83 | PARP1 (0.48) | PARP1PIM1PIM3AURKB | |
| SCHEMBL7141034 | 0.83 | PARP1 (0.72) | PARP1 | |
| SCHEMBL7139317 | 0.81 | PARP1 (0.58) | PARP1PIM1PIM3AURKB | |
| SCHEMBL7132446 | 0.80 | PARP1 (0.59) | PARP1PIM1PIM3AURKB | |
| SCHEMBL29696369 | 0.79 | NPC1 (0.53) | PARP1CYP3A4CYP2C9 | |
| SCHEMBL7137491 | 0.78 | PARP1 (0.47) | PARP1 | |
| SCHEMBL3585144 | 0.78 | PARP1 (0.64) | PARP1PIM1AURKB | |
| SCHEMBL3579908 | 0.77 | PARP1 (0.61) | PARP1PIM1PIM3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509365-B1 | 2-phenylbenzimidazoles and 2-phenylindoles, and production and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-21 | — | — | US | disclosed |