Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130614 | 0.86 | LMNA (0.45) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL7136768 | 0.86 | CAPN1 (0.41) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7137508 | 0.85 | LMNA (0.44) | HTTKMT2ALMNASMN1; SMN2SLC1A3 | |
| SCHEMBL3951175 | 0.83 | HTT (0.56) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7133730 | 0.82 | CTSL (0.43) | MEN1KMT2ALMNASMN1; SMN2CASP1 | |
| SCHEMBL7133716 | 0.81 | SLC1A3 (0.47) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL7511539 | 0.81 | HTT (0.67) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7130913 | 0.80 | HTT (0.47) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL7134210 | 0.78 | MMP3 (0.51) | SMN1; SMN2FOLH1CASP1 | |
| SCHEMBL7514786 | 0.77 | HTT (0.73) | HTTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506733-B1 | Which process comprises hydrogenating a compound of Formula 9: presence of a catalytic amount of 20% palladium hydroxide on carbon. | AXYS PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | disclosed |