Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17374759 | 0.80 | — | — | |
| SCHEMBL5483124 | 0.75 | — | — | |
| SCHEMBL17374754 | 0.74 | LDHA (0.36) | — | |
| SCHEMBL11042064 | 0.69 | MRGPRX2 (0.50) | MRGPRX2PRKD1 | |
| SCHEMBL10894116 | 0.69 | MRGPRX2 (0.46) | MRGPRX2PRKD1 | |
| SCHEMBL3293896 | 0.67 | CA1 (0.32) | — | |
| SCHEMBL6238119 | 0.66 | — | — | |
| SCHEMBL1091415 | 0.64 | KDM4E (0.33) | MAPK1 | |
| SCHEMBL4807544 | 0.62 | — | — | |
| SCHEMBL4961936 | 0.61 | MRGPRX2 (0.45) | MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853610-B1 | SYNTHESIS AND USE OF RETINOID COMPOUNDS HAVING NEGATIVE HORMONE AND/OR ANTAGONIST ACTIVITIES | ALLERGAN SALES INC (US) | 2003-03-05 | — | — | EP | disclosed |