Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136996 | 0.74 | MRGPRX2 (0.42) | — | |
| SCHEMBL17374759 | 0.70 | — | — | |
| SCHEMBL5483124 | 0.66 | — | — | |
| SCHEMBL11512072 | 0.62 | MAOA (0.43) | KDM4ESLC6A4SLC6A2SLC6A3CA1 | |
| SCHEMBL3293896 | 0.59 | CA1 (0.32) | CA1 | |
| SCHEMBL1436765 | 0.59 | HPGD (0.59) | HPGDSLC6A4SLC6A2SLC6A3CXCL8 | |
| SCHEMBL9282009 | 0.59 | LMNA (0.47) | LDHAHPGDSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17374755 | 0.58 | LDHA (0.41) | LDHAHPGDKDM4ESLC6A4SLC6A2 | |
| SCHEMBL21452232 | 0.58 | TP53 (0.44) | CA1 | |
| SCHEMBL6238119 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160952-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015200709-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2015-12-30 | — | — | WO | disclosed |