Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226371 | 1.00 | HTR7 (0.49) | HTR7HTR2BALDH1A1NPC1RAB9A | |
| SCHEMBL942131 | 0.89 | TSHR (0.39) | HTR7HTR2BALDH1A1NPC1RAB9A | |
| SCHEMBL30410319 | 0.82 | HTR2A (0.52) | HTR7HTR2BALDH1A1POLBMEN1 | |
| SCHEMBL353865 | 0.82 | HTR2A (0.52) | HTR7HTR2BALDH1A1POLBMEN1 | |
| SCHEMBL29444048 | 0.82 | HTR2A (0.52) | HTR7HTR2BALDH1A1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL355946 | 0.79 | HTR2A (0.50) | HTR7HTR2BPOLBHTR2AGPR3 | |
| Water SCHEMBL28455469 | 0.79 | HTR2A (0.50) | HTR7HTR2BALDH1A1POLBMEN1 | |
| SCHEMBL22270015 | 0.79 | HTR2A (0.50) | HTR7HTR2BALDH1A1NPC1RAB9A | |
| Bromide SCHEMBL4922157 | 0.79 | HTR2A (0.50) | HTR7HTR2BALDH1A1POLBMEN1 | |
| SCHEMBL1075715 | 0.78 | HTR2B (0.51) | HTR7HTR2BALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189929-B1 | FACTOR VIIA INHIBITORS | AVENTIS PHARMA GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6500803-B1 | Factor VIIa inhibitors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1189929-A2 | FACTOR VIIA INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075172-A2 | FACTOR VIIa INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-14 | — | — | WO | disclosed |
| EP-1059302-A1 | Factor VIIa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2000-12-13 | — | — | EP | disclosed |