SCHEMBL226371

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7137182	1.00	HTR7 (0.49)	HTR7HTR2BALDH1A1NPC1RAB9A
	SCHEMBL942131	0.89	TSHR (0.39)	HTR7HTR2BALDH1A1NPC1RAB9A
	SCHEMBL30410319	0.82	HTR2A (0.52)	HTR7HTR2BALDH1A1POLBMEN1
	SCHEMBL353865	0.82	HTR2A (0.52)	HTR7HTR2BALDH1A1POLBMEN1
	SCHEMBL29444048	0.82	HTR2A (0.52)	HTR7HTR2BALDH1A1POLBMEN1
	Hydrochloric Acid SCHEMBL355946	0.79	HTR2A (0.50)	HTR7HTR2BPOLBHTR2AGPR3
	Water SCHEMBL28455469	0.79	HTR2A (0.50)	HTR7HTR2BALDH1A1POLBMEN1
	SCHEMBL22270015	0.79	HTR2A (0.50)	HTR7HTR2BALDH1A1NPC1RAB9A
	Bromide SCHEMBL4922157	0.79	HTR2A (0.50)	HTR7HTR2BALDH1A1POLBMEN1
	SCHEMBL1075715	0.78	HTR2B (0.51)	HTR7HTR2BALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.