Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132288 | 0.92 | LMNA (0.47) | LMNAMAPTCYP19A1NR3C1HIF1A | |
| SCHEMBL7187631 | 0.92 | LMNA (0.47) | LMNAMAPTCYP19A1NR3C1HIF1A | |
| Bicarbonate SCHEMBL7130344 | 0.87 | LMNA (0.42) | LMNAMAPTCYP19A1NR3C1HIF1A | |
| SCHEMBL7136967 | 0.86 | LMNA (0.48) | LMNAMAPTCYP19A1NR3C1HIF1A | |
| SCHEMBL7135801 | 0.83 | LMNA (0.49) | LMNAMAPTCYP19A1NR3C1HIF1A | |
| SCHEMBL8587966 | 0.82 | LMNA (0.54) | LMNAMAPTCYP19A1NR3C1HIF1A | |
| SCHEMBL5672145 | 0.81 | LMNA (0.52) | LMNAMAPTCYP19A1NR3C1HIF1A | |
| SCHEMBL7877720 | 0.81 | LMNA (0.52) | LMNAMAPTCYP19A1NR3C1HIF1A | |
| SCHEMBL7204662 | 0.79 | LMNA (0.51) | LMNAMAPTCYP19A1NR3C1HIF1A | |
| SCHEMBL30915294 | 0.77 | LMNA (0.48) | LMNAMAPTCYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003062259-A2 | NON-AROMATIC 17.ALPHA.-ESTERS OF ANDROSTANE-17.BETA.-CARBOXYLATE ESTERS AS ANTI-INFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 2003-07-31 | — | — | WO | disclosed |