Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12386592 | 0.75 | BRD4 (0.32) | — | |
| SCHEMBL2754568 | 0.75 | LMNA (0.33) | POLB | |
| SCHEMBL18465650 | 0.70 | — | — | |
| SCHEMBL19258843 | 0.70 | — | — | |
| SCHEMBL24564940 | 0.70 | — | — | |
| SCHEMBL12146257 | 0.70 | — | — | |
| SCHEMBL7136943 | 0.68 | MGLL (0.39) | — | |
| SCHEMBL7209074 | 0.67 | POLB (0.35) | POLB | |
| SCHEMBL15462789 | 0.67 | ATAD2 (0.31) | — | |
| SCHEMBL23512721 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509001-B1 | Peptide covalently linked to radioactive metal or iodine chelator; diagnostic and therapeutic modalities against cancer; lung and ovarian adenocarcinoma, breast cancers and lymphomas | DIATIDE, INC. | 2003-01-21 | — | — | US | disclosed |
| US-6479032-B1 | Calcitonin receptor binding reagents | DIATIDE, INC. | 2002-11-12 | — | — | US | disclosed |
| US-6086850-A | SYNTHETIC CALCITONIN RECEPTOR-BINDING COMPOUND OF GIVEN MOLECULAR WEIGHT COVALENTLY LINKED TO A RADIOMETAL CHELATOR TO FORM A REAGENT HAVING A BINDING AFFINITY FOR A CALCITONIN RECEPTOR GREATER OR EQUAL TO RADIOIODINATED NATIVE CALCITONIN | DIATIDE, INC. (US) | 2000-07-11 | — | — | US | disclosed |
| US-6083480-A | RADIOTHERAPEUTIC REAGENTS AND PEPTIDES, RADIODIAGNOSTIC REAGENTS AND PEPTIDES | DIATIDE, INC. (US) | 2000-07-04 | — | — | US | disclosed |