Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL27713117 | 1.00 | FFAR4 (0.57) | FFAR4FFAR1GPR84PPARGPPARD | |
| Behenic Acid SCHEMBL28358122 | 0.92 | GPR84 (0.65) | FFAR4FFAR1GPR84PPARGPPARD | |
| Octanoic Acid SCHEMBL31240956 | 0.92 | GPR84 (0.65) | FFAR4FFAR1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL3379301 | 0.92 | GPR84 (0.65) | FFAR4FFAR1GPR84PPARGPPARD | |
| Palmitic Acid SCHEMBL15066461 | 0.90 | GPR84 (0.63) | FFAR4FFAR1GPR84PPARGPPARD | |
| Nonanoate SCHEMBL25413167 | 0.88 | FFAR4 (0.71) | FFAR4FFAR1GPR84PPARGPPARD | |
| Nonadecanoic Acid SCHEMBL25413354 | 0.88 | FFAR4 (0.71) | FFAR4FFAR1GPR84PPARGPPARD | |
| Behenic Acid SCHEMBL2476772 | 0.88 | FFAR4 (0.71) | FFAR4FFAR1GPR84PPARGPPARD | |
| Octanoic Acid SCHEMBL23904156 | 0.88 | FFAR4 (0.71) | FFAR4FFAR1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL21409842 | 0.88 | FFAR4 (0.71) | FFAR4FFAR1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 613 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120321576-A1 | SUNSCREEN COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2012-12-20 | — | — | US | claimed |
| EP-4687818-A1 | COMPOSITION COMPRISING AN ALKYL- AND/OR ALKENYLGLYCOSIDE | KAO CORPORATION, S.A. (ES) | 2026-02-11 | — | — | EP | disclosed |
| EP-4019616-B1 | QUATERNARY ESTER AMMONIUM COMPOUND COMPOSITIONS | KAO CORP SA (ES) | 2026-01-28 | — | — | EP | disclosed |
| EP-4682106-A1 | FATTY ACID-TREATED ZINC OXIDE PARTICLES, METHOD FOR PRODUCING SAME, AND DISPERSION AND COSMETIC HAVING SAME BLENDED THEREIN | Sakai Chemical Industry Co., Ltd. (JP) | 2026-01-21 | — | — | EP | disclosed |
| US-20250319011-A1 | COMPOSITION COMPRISING AN ALKYL AND/OR ALKENYLGLYCOSIDE DERIVATIVE AND AN ESTER DERIVED FROM A HYDROXYCARBOXYLIC ACID AND A FATTY ALCOHOL | KAO CORP SA (ES) | 2025-10-16 | — | — | US | disclosed |
| EP-3162359-B2 | OIL-IN-WATER EMULSION COMPOSITION | SHISEIDO CO LTD (JP) | 2025-07-02 | — | — | EP | disclosed |
| EP-4563680-A1 | SOLID PERSONAL CARE OR DETERGENT COMPOSITION | Dalli-Werke GmbH & Co. KG (DE) | 2025-06-04 | — | — | EP | disclosed |
| US-12318467-B2 | Cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2025-06-03 | — | — | US | disclosed |
| WO-2025105415-A1 | MELANOGENESIS INHIBITOR AND EXTERNAL PREPARATION FOR SKIN CONTAINING SAME | 三菱瓦斯化学株式会社 | 2025-05-22 | — | — | WO | disclosed |
| EP-3556344-B1 | COSMETIC COMPOSITIONS | KAO CORP SA (ES) | 2025-04-16 | — | — | EP | disclosed |
| US-5853705-A | Anti-aging cosmetic composition | SHISEIDO COMPANY, LTD. (JP) | 1998-12-29 | — | — | US | disclosed |
| EP-0852949-A2 | Use of alpha-amino-acids for enhancing desmosomal degradation or stratum corneum desquamation | SHISEIDO COMPANY LIMITED (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5747049-A | AMINOETHYLSULFINIC ACID OR AMINOETHYLTHIOSULFONIC ACID, SUNSCREEN | SHISEIDO COMPANY, LTD. (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0815838-A2 | External skin treatment composition | SHISEIDO COMPANY, LTD. (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0797984-A2 | Anti-aging cosmetic composition | SHISEIDO COMPANY LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |
| EP-0688559-A1 | Skin anti-ageing composition | SHISEIDO COMPANY LIMITED (JP) | 1995-12-27 | — | — | EP | disclosed |
| EP-0487404-B1 | External dermatological composition | HAYASHIBARA BIOCHEM LAB (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0487404-A1 | External dermatological composition | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4897261-A | ORGANIC SOLVENTS, OIL AND WATER SOLUBLE POLYMERS,MOISTURIZERS, HYDROPHILIC AND LIPOPHILIC COMPONENTS | SHISEIDO COMPANY LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0291555-A1 | Fingernail cosmetic composition | SHISEIDO COMPANY LIMITED (JP) | 1988-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250319011-A1 | COMPOSITION COMPRISING AN ALKYL AND/OR ALKENYLGLYCOSIDE DERIVATIVE AND AN ESTER DERIVED FROM A HYDROXYCARBOXYLIC ACID AND A FATTY ALCOHOL | ALKBH3, CUTA, FASN | FFAR4 82/4885FFAR1 73/4885GPR84 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.