SCHEMBL7138459

SCHEMBL7138459

COC(=O)c1ccccc1-c1cccc(OC(=O)O)c1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 5/20 0.55
SLC6A4 P31645 3/20 0.50
KMT2A Q03164 3/20 0.46
HTT P42858 2/20 0.46
MAPT P10636 2/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
SLC6A2 P23975 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 2/20 0.44
LMNA P02545 1/20 0.44
MEN1 O00255 1/20 0.43
MAPK10 P53779 1/20 0.43
PTK2B Q14289 1/20 0.43
NCOA1 Q15788 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
HSD17B10 Q99714 2/20 0.43
PTGER1 P34995 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1638900 0.88 SLC6A3 (0.61) SLC6A3SLC6A4KMT2AHTTMAPT
SCHEMBL3932901 0.84 SLC6A3 (0.74) SLC6A3SLC6A4KMT2AHTTMAPT
SCHEMBL4657202 0.83 SLC6A3 (0.50) SLC6A3SLC6A4KMT2AHTTMAPT
SCHEMBL12724753 0.81 SLC6A3 (0.57) SLC6A3SLC6A4KMT2AHTTMAPT
Biphenyl SCHEMBL6812918 0.80 SLC6A3 (0.68) SLC6A3SLC6A4KMT2AHTTMAPT
SCHEMBL6439194 0.79 SLC6A3 (0.48) SLC6A3SLC6A4KMT2AHTTMAPT
SCHEMBL69464 0.79 SLC6A3 (0.67) SLC6A3SLC6A4KMT2AHTTMAPT
SCHEMBL7047572 0.78 PDCD1 (0.49) HTTMAPTKDM4EALDH1A1L3MBTL1
SCHEMBL19849652 0.77 TSHR (0.53) SLC6A3SLC6A4KMT2AHTTMAPT
SCHEMBL29634134 0.77 TSHR (0.53) SLC6A3SLC6A4KMT2AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6509435-B1 Heat resistance, stability; moldings TEIJIN LIMITED (JP) 2003-01-21 US disclosed
EP-1191049-A1 POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-03-27 EP disclosed