Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138590 | 1.00 | MAOB (0.41) | MAOBLMNAMAPTGAAATM | |
| SCHEMBL7136429 | 0.91 | MAOB (0.41) | MAOBLMNAMAPTGAAATM | |
| SCHEMBL7136425 | 0.91 | MAOB (0.41) | MAOBLMNAMAPTGAAATM | |
| SCHEMBL7140184 | 0.89 | MAOB (0.43) | MAOBLMNAMAPTGAAATM | |
| SCHEMBL7140189 | 0.89 | MAOB (0.43) | MAOBLMNAMAPTGAAATM | |
| SCHEMBL7136717 | 0.89 | MAOB (0.51) | MAOBLMNAMAPTGAAATM | |
| SCHEMBL7135385 | 0.85 | TRPA1 (0.42) | MAOBCYP1A1CYP1B1 | |
| SCHEMBL7135382 | 0.85 | TRPA1 (0.42) | MAOBCYP1A1CYP1B1 | |
| SCHEMBL7144373 | 0.85 | MAOB (0.44) | MAOBLMNAMAPTNPSR1MEN1 | |
| SCHEMBL7144375 | 0.85 | MAOB (0.44) | MAOBLMNAMAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996439-B1 | BETA-ALKOXYACRYLATES AGAINST MALARIA | HOFFMANN LA ROCHE (CH) | 2003-01-08 | — | — | EP | claimed |