Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144373 | 1.00 | MAOB (0.44) | MAOBKDM4EMEN1KMT2AMAPT | |
| SCHEMBL7135382 | 0.88 | TRPA1 (0.42) | MAOBNFE2L2 | |
| SCHEMBL7135385 | 0.88 | TRPA1 (0.42) | MAOBNFE2L2 | |
| SCHEMBL7141749 | 0.85 | AKR1C2 (0.44) | MAOBMEN1KMT2AMAPTNFE2L2 | |
| SCHEMBL7141751 | 0.85 | AKR1C2 (0.44) | MAOBMEN1KMT2AMAPTNFE2L2 | |
| SCHEMBL7138590 | 0.85 | MAOB (0.41) | MAOBMEN1KMT2AMAPTLMNA | |
| SCHEMBL7138593 | 0.85 | MAOB (0.41) | MAOBMEN1KMT2AMAPTLMNA | |
| SCHEMBL7139096 | 0.85 | MAOB (0.42) | MAOBMEN1KMT2ALMNANFE2L2 | |
| SCHEMBL7139094 | 0.85 | MAOB (0.42) | MAOBMEN1KMT2ALMNANFE2L2 | |
| SCHEMBL7141545 | 0.83 | MAOB (0.43) | MAOBMEN1KMT2ALMNANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996439-B1 | BETA-ALKOXYACRYLATES AGAINST MALARIA | HOFFMANN LA ROCHE (CH) | 2003-01-08 | — | — | EP | disclosed |
| US-6084120-A | ACTIVE AGAINST CHLOROQUINE-SENSITIVE PATIENTS AND AGAINST CHLOROQUINE-RESISTANT MALARIA PATHOGENS; PROPHYLAXIS AND TREATMENT; E.G., A 3 METHOXY-2-(2-(4-PHENYLBUTA-1,3-DIEN-1-YL)PHENYL)ACRYLIC ACID | HOFFMANN-LA ROCHE INC. (US) | 2000-07-04 | — | — | US | disclosed |