⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL20545911 | 0.97 | — | — | |
| SCHEMBL7920635 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL5860713 | 0.78 | — | — | |
| SCHEMBL27410727 | 0.78 | — | — | |
| SCHEMBL9418547 | 0.75 | — | — | |
| SCHEMBL1826109 | 0.75 | LIPA (0.36) | — | |
| SCHEMBL183178 | 0.72 | PLOD2 (0.46) | — | |
| SCHEMBL11533523 | 0.72 | FAAH (0.57) | — | |
| SCHEMBL9157169 | 0.71 | FAAH (0.56) | — | |
| SCHEMBL10176683 | 0.71 | TRPA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6083 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977918-A | Synthesis method of 2-bromomethyl-5-trifluoromethyl furan | 上海高准医药有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-110272400-B | Synthesis method of 2-trifluoromethyl substituted furan compound and derivative thereof | 福州大学 | 2022-08-23 | — | — | CN | claimed |
| CN-114395111-A | Preparation method of anion exchange membrane imitating chemical structure of main side chain of Nafion | 武汉理工大学 | 2022-04-26 | — | — | CN | claimed |
| CN-114247310-A | Hollow fiber ultrafiltration membrane of polyaromatic hydrocarbon alkylidene macromolecule | 厦门大学 | 2022-03-29 | — | — | CN | claimed |
| CN-113307724-A | 1-trifluoromethyl cinnamyl alcohol derivative and preparation method and application thereof | 海南大学 | 2021-08-27 | — | — | CN | claimed |
| CN-107406375-B | Process for producing unsaturated ketone compound | 埃维克辛公司 | 2020-09-15 | — | — | CN | claimed |
| CN-110272400-A | The synthetic method of 2- trifluoromethyl substituted furan compound and its derivative | 福州大学 | 2019-09-24 | — | — | CN | claimed |
| EP-3247700-B1 | PROCESS FOR THE PREPARATION OF A POLYUNSATURATED KETONE COMPOUND | AVEXXIN AS (NO) | 2019-03-20 | — | — | EP | claimed |
| US-10183911-B2 | Process for the preparation of a polyunsaturated ketone compound | AVEXXIN AS (NO) | 2019-01-22 | — | — | US | claimed |
| EP-3398936-A1 | PROCESS FOR THE PREPARATION OF A POLYUNSATURATED KETONE COMPOUND | Avexxin AS (NO) | 2018-11-07 | — | — | EP | claimed |
| CN-103497182-A | 3,4-dichloro isothiazole derivative containing 4,5-dihydro thiazole alkyd resin and preparation method and application thereof | UNIV NANKAI | 2014-01-08 | — | — | CN | claimed |
| CN-103214474-A | 5-methyl-1,2,3-thiadiazole derivatives containing 4,5-dihydrothiazole alcohol acid esters and preparation methods and application thereof | UNIV NANKAI | 2013-07-24 | — | — | CN | claimed |
| US-20130041054-A1 | MATERIAL FOR REMOVING CAUXIN IN CAT URINE | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY | 2013-02-14 | — | — | US | claimed |
| EP-2538216-A1 | MATERIAL FOR REMOVING CAUXIN IN CAT URINE | National University Corporation Chiba University (JP) | 2012-12-26 | — | — | EP | claimed |
| EP-1640380-B1 | HISTONE DEACETYLASE INHIBITOR AND PROCESS FOR PRODUCING THE SAME | RIKEN (JP) | 2010-03-10 | — | — | EP | claimed |
| US-7662778-B2 | a compound containing cyclic tetrapeptide coupled to amide, ester, ketone groups; apoptosis and cell differentiation inducer; cancer metastasis and angiogenesis inhibitor; catalytic hydrogenation, acid treatment, fluoride anion treatment, or hydrolysis for deblocking; coupling cyclic tertrapeptide | RIKEN (JP) | 2010-02-16 | — | — | US | claimed |
| US-20070185071-A1 | Histone deacetylase inhibitor and process for producing the same | RIKEN (JP) | 2007-08-09 | — | — | US | claimed |
| EP-1640380-A1 | HISTONE DEACETYLASE INHIBITOR AND PROCESS FOR PRODUCING THE SAME | Riken (JP) | 2006-03-29 | — | — | EP | claimed |
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | claimed |