Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA4 | P22748 | 3/20 | 0.55 |
| ▸ | CA6 | P23280 | 3/20 | 0.55 |
| ▸ | CA5A | P35218 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | DPP4 | P27487 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968964 | 1.00 | CA12 (0.55) | CA12CA1CA4CA6CA5A | |
| SCHEMBL3559802 | 0.85 | HCAR2 (0.59) | CA12CA1CA4CA6CA5A | |
| SCHEMBL3559806 | 0.85 | HCAR2 (0.59) | CA12CA1CA4CA6CA5A | |
| SCHEMBL3225302 | 0.83 | HDAC3 (0.67) | CA12CA1CA4CA6CA5A | |
| SCHEMBL3458431 | 0.83 | CA12 (0.57) | CA12CA1CA4CA6CA5A | |
| SCHEMBL23854259 | 0.83 | HDAC3 (0.67) | CA12CA1CA4CA6CA5A | |
| SCHEMBL583193 | 0.83 | CA12 (0.57) | CA12CA1CA4CA6CA5A | |
| SCHEMBL18422478 | 0.82 | HDAC3 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18422480 | 0.82 | HDAC3 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15059069 | 0.81 | CA12 (0.55) | CA12CA1CA4CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505733-B2 | Single step enantioselective process for the preparation of 3-substituted chiral phthalides | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-11-29 | — | — | US | disclosed |
| US-20150299154-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-10-22 | — | — | US | disclosed |
| US-9073887-B2 | Single step enantioselective process for the preparation of 3-substituted chiral phthalides | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | disclosed |
| CN-104371071-A | Preparation method for hyperbranched polycarboxylic-acid concrete efficient water reducer | JIANGSU SUBOTE NEW MAT CO LTD | 2015-02-25 | — | — | CN | disclosed |
| US-20140330027-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-11-06 | — | — | US | disclosed |
| WO-2013072830-A9 | A SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-02-20 | — | — | WO | disclosed |
| WO-2013072830-A1 | A SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | WO | disclosed |
| US-6509506-B1 | Asymmetric aminohydroxylation of olefins using osmium catalyst; oxidation | THE SCRIPPS RESEARCH INSTITUTE | 2003-01-21 | — | — | US | disclosed |
| US-5994583-A | Two step synthesis of D- and L- α-amino acids and D- and L- α-amino-aldehydes | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-11-30 | — | — | US | disclosed |
| US-5859281-A | Catalytic asymmetric aminohydroxylation of olefins with sulfonamides | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997044312-A9 | TWO STEP SYNTHESIS OF D- AND L- α-AMINO ACIDS AND D- AND L- α-AMINO ALDEHYDES | — | 1998-03-12 | — | — | WO | disclosed |
| WO-1997044312-A1 | TWO STEP SYNTHESIS OF D- AND L- α-AMINO ACIDS AND D- AND L- α-AMINO ALDEHYDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330027-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | PPOX, NFE2L2, CBR1 | CA12 1703/4885CA1 2564/4885CA4 194/4885 |
| US-20150299154-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | PPOX, NFE2L2, CBR1 | CA12 1703/4885CA1 2564/4885CA4 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.