Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDH1 | P12830 | 1/20 | 0.51 |
| ▸ | APC | P25054 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 4/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26986678 | 0.83 | ALDH1A1 (0.67) | ALDH1A1ADORA2AADORA1KDM4ELMNA | |
| SCHEMBL30712644 | 0.83 | ALDH1A1 (0.67) | ALDH1A1ADORA2AADORA1KDM4ELMNA | |
| SCHEMBL29233402 | 0.81 | DHODH (0.44) | CDH1APCCTNNB1TCF7L2KMO | |
| SCHEMBL4676256 | 0.77 | CDH1 (0.57) | CDH1APCCTNNB1TCF7L2KMO | |
| SCHEMBL25210699 | 0.76 | KMO (0.55) | CDH1APCCTNNB1TCF7L2KMO | |
| SCHEMBL11864615 | 0.73 | ADORA2A (0.47) | CDH1APCCTNNB1TCF7L2ADORA2A | |
| SCHEMBL11862459 | 0.72 | ADORA2A (0.50) | CDH1APCCTNNB1TCF7L2ALDH1A1 | |
| SCHEMBL6182981 | 0.72 | KMO (0.54) | CDH1APCCTNNB1TCF7L2KMO | |
| SCHEMBL4680695 | 0.71 | CDH1 (0.51) | CDH1APCCTNNB1TCF7L2KMO | |
| SCHEMBL13108726 | 0.71 | NPSR1 (0.59) | ALDH1A1ADORA2AADORA1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084930-A1 | DIPHENYLPYRIDINE DERIVATIVES, THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2003-10-16 | — | — | WO | disclosed |