SCHEMBL714064

SCHEMBL714064

O=C(O)c1c(F)c(F)c(Oc2c(F)c(F)c(Oc3c(F)c(F)c(C(=O)O)c(C(=O)O)c3F)c(F)c2F)c(F)c1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.37
KMT2A Q03164 6/20 0.37
CYP2C9 P11712 2/20 0.37
CYP1A2 P05177 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.35
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
GFER P55789 1/20 0.33
HSD17B10 Q99714 1/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405294 1.00 MEN1 (0.37) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2
SCHEMBL3646838 1.00 MEN1 (0.37) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2
SCHEMBL20262187 0.95 MEN1 (0.35) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2
SCHEMBL8576244 0.93 MEN1 (0.34) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2
SCHEMBL712618 0.93 MEN1 (0.34) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2
SCHEMBL4594690 0.91 MEN1 (0.33) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2
SCHEMBL22766208 0.90 MEN1 (0.37) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2
SCHEMBL3341200 0.89 CES2 (0.38) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2
SCHEMBL29404409 0.89 CES2 (0.38) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2
SCHEMBL29962959 0.88 MEN1 (0.36) MEN1KMT2ACYP2C9CYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1382644-B1 Photosensitive polyimide resin precursor composition, optical waveguide using the polyimide and process for producing the optical waveguide NITTO DENKO CORP (JP) 2007-09-12 EP claimed
US-7037637-B2 Photosensitive polyimide resin precursor composition, optical polyimide obtained from the composition, optical waveguide using the polyimide, and process for producing the optical waveguide NITTO DENKO CORPORATION (JP) 2006-05-02 US claimed
US-20040013953-A1 Photosensitive polyimide resin precursor composition, optical polyimide obtained from the composition, optical waveguide using the polyimide, and process for producing the optical waveguide NITTO DENKO CORPORATION 2004-01-22 US claimed
EP-1382644-A1 Photosensitive polyimide resin precursor composition, optical waveguide using the polyimide and process for producing the optical waveguide NITTO DENKO CORPORATION (JP) 2004-01-21 EP claimed
US-5849934-A Method for preparing aromatic compounds NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1998-12-15 US claimed
US-5750731-A POLYIMIDE ANHYDRIDE MONOMERS NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) 1998-05-12 US claimed
EP-0480266-B1 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH & TELEPHONE (JP) 1996-06-26 EP claimed
EP-0480266-A2 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-15 EP claimed
JP-5001148-A None JP disclosed
JP-9110784-A None JP disclosed
JP-4314732-A None JP disclosed
JP-4328133-A None JP disclosed
JP-9031014-A None JP disclosed
JP-9110785-A None JP disclosed
US-5233018-A Heat resistance and low optical transmission loss in the near-infrared region; integrated circuits NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1993-08-03 US disclosed
JP-H051148-A TOTALLY FLUORINATED POLYIMIDE, ITS INTERMEDIATE AND STARTING SUBSTANCE, THEIR PRODUCTION AND OPTICAL MATERIAL MADE OF THE TOTALLY FLUORINATED POLYIMIDE NIPPON TELEGR & TELEPH CORP <NTT> 1993-01-08 JP disclosed
JP-H04328133-A POLYIMIDE RESIN THIN FILM NIPPON TELEGR & TELEPH CORP <NTT> 1992-11-17 JP disclosed
JP-H04314732-A FLUORINATED POLYAMIC ACID, FLUORINATED POLYIMIDE, AND THEIR PRODUCTION NIPPON TELEGR & TELEPH CORP <NTT> 1992-11-05 JP disclosed
EP-0480266-A2 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-15 EP disclosed
EP-0480266-A2 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-15 EP disclosed