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SCHEMBL8576244

SCHEMBL8576244

O=C(O)c1c(C(=O)O)c(F)c2c(F)c(C(=O)O)c(C(=O)O)c(F)c2c1F.O=C(O)c1c(F)c(F)c(Oc2c(F)c(F)c(Oc3c(F)c(F)c(C(=O)O)c(C(=O)O)c3F)c(F)c2F)c(F)c1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ CYP2C9 P11712 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ HPGD P15428 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ TSHR P16473 2/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ GFER P55789 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405294 0.93 MEN1 (0.37) MEN1KMT2ACYP2C9CYP1A2HPGD
SCHEMBL714064 0.93 MEN1 (0.37) MEN1KMT2ACYP2C9CYP1A2HPGD
SCHEMBL3646838 0.93 MEN1 (0.37) MEN1KMT2ACYP2C9CYP1A2HPGD
SCHEMBL20262187 0.89 MEN1 (0.35) MEN1KMT2ACYP2C9CYP1A2HPGD
SCHEMBL712618 0.87 MEN1 (0.34) MEN1KMT2ACYP2C9CYP1A2HPGD
SCHEMBL4594690 0.85 MEN1 (0.33) MEN1KMT2ACYP2C9CYP1A2HPGD
SCHEMBL22766208 0.84 MEN1 (0.37) MEN1KMT2ACYP2C9CYP1A2HPGD
SCHEMBL29404409 0.83 CES2 (0.38) MEN1KMT2ACYP2C9CYP1A2HPGD
SCHEMBL3341200 0.83 CES2 (0.38) MEN1KMT2ACYP2C9CYP1A2HPGD
SCHEMBL29962959 0.82 MEN1 (0.36) MEN1KMT2ACYP2C9CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750731-A POLYIMIDE ANHYDRIDE MONOMERS NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) 1998-05-12 — — US disclosed