Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 8/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140663 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CASP1TACR1GPR34CTSL | |
| SCHEMBL3919350 | 0.85 | ALDH1A1 (0.52) | ALDH1A1CASP1ITGB3ITGA2B | |
| SCHEMBL10887038 | 0.85 | ALDH1A1 (0.52) | ALDH1A1CASP1ITGB3ITGA2B | |
| SCHEMBL6022077 | 0.85 | ALDH1A1 (0.52) | ALDH1A1CASP1ITGB3ITGA2B | |
| SCHEMBL2977396 | 0.84 | ALDH1A1 (0.63) | ALDH1A1CASP1ITGB3ITGA2B | |
| SCHEMBL2966988 | 0.84 | ALDH1A1 (0.63) | ALDH1A1CASP1ITGB3ITGA2B | |
| SCHEMBL10884777 | 0.84 | ALDH1A1 (0.63) | ALDH1A1CASP1ITGB3ITGA2B | |
| SCHEMBL2263701 | 0.84 | ALDH1A1 (0.51) | ALDH1A1CASP1GPR34ITGB1ITGA4 | |
| SCHEMBL29908104 | 0.84 | TGM2 (0.52) | ALDH1A1CASP1GPR34CTSSCTSK | |
| SCHEMBL19732325 | 0.84 | ALDH1A1 (0.51) | ALDH1A1CASP1ITGB3ITGA2BITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189929-B1 | FACTOR VIIA INHIBITORS | AVENTIS PHARMA GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6500803-B1 | Factor VIIa inhibitors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1189929-A2 | FACTOR VIIA INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075172-A2 | FACTOR VIIa INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-14 | — | — | WO | disclosed |
| EP-1059302-A1 | Factor VIIa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2000-12-13 | — | — | EP | disclosed |