SCHEMBL2977396

SCHEMBL2977396

C=CCOC(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.63
CASP1 P29466 9/20 0.60
MME P08473 1/20 0.51
TYR P14679 1/20 0.51
ITGB3 P05106 4/20 0.50
ITGA2B P08514 4/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2966988 1.00 ALDH1A1 (0.63) ALDH1A1CASP1MMETYRITGB3
SCHEMBL10884777 1.00 ALDH1A1 (0.63) ALDH1A1CASP1MMETYRITGB3
SCHEMBL3917891 0.89 PPARG (0.62) CASP1MMEITGB3ITGA2B
SCHEMBL27677478 0.89 PPARG (0.62) CASP1MMEITGB3ITGA2B
SCHEMBL10887038 0.89 ALDH1A1 (0.52) ALDH1A1CASP1MMETYRITGB3
SCHEMBL3919350 0.89 ALDH1A1 (0.52) ALDH1A1CASP1MMETYRITGB3
SCHEMBL10882804 0.89 ALDH1A1 (0.60) ALDH1A1CASP1
SCHEMBL6022077 0.89 ALDH1A1 (0.52) ALDH1A1CASP1MMETYRITGB3
SCHEMBL13205564 0.89 ALDH1A1 (0.67) ALDH1A1CASP1
SCHEMBL10458275 0.89 ALDH1A1 (0.67) ALDH1A1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12625431-B2 EUV resist underlayer film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2026-05-12 US disclosed
WO-2024043313-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, MICROENCAPSULATED PIGMENT USING SAID REVERSIBLE THERMOCHROMIC COMPOSITION, WRITING TOOL, AND TOY 三菱ケミカル株式会社 2024-02-29 WO disclosed
US-20230391818-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-12-07 US disclosed
EP-4242219-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-13 EP disclosed
US-20230098881-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-03-30 US disclosed
CN-115053184-A Composition for forming EUV resist underlayer film 日产化学株式会社 2022-09-13 CN disclosed
US-7767811-B2 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids BRANDEIS UNIVERSITY (US) 2010-08-03 US disclosed
US-20060293536-A1 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids BRANDEIS UNIVERSITY (US) 2006-12-28 US disclosed
US-7057038-B2 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids BRANDEIS UNIVERSITY (US) 2006-06-06 US disclosed
EP-1419125-A4 KINETIC RESOLUTIONS OF CHIRAT 3- AND 3-SUBSTITUTED CARBOXYLIC ACIDS UNIV BRANDEIS (US) 2005-03-23 EP disclosed
US-6562967-B2 Drug screening; purity BRANDEIS UNIVERSITY 2003-05-13 US disclosed
EP-1305270-A1 KINETIC RESOLUTIONS OF CHIRAL 2- AND 3-SUBSTITUTED CARBOXYLIC ACIDS Brandeis University (US) 2003-05-02 EP disclosed
WO-2003011799-A1 KINETIC RESOLUTIONS OF CHIRAT 3- AND 3-SUBSTITUTED CARBOXYLIC ACIDS BRANDEIS UNIVERSITY (US) 2003-02-13 WO disclosed
US-20020165393-A1 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-11-07 US disclosed
US-20020151744-A1 Kinetic resolutions of chiral 2-and-3-substituted carboxylic acids NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-10-17 US disclosed
WO-2002010096-A1 KINETIC RESOLUTIONS OF CHIRAL 2- AND 3-SUBSTITUTED CARBOXYLIC ACIDS BRANDEIS UNIVERSITY (US) 2002-02-07 WO disclosed
US-6156889-A Reagent useful for cleaving a protected functional group RHODIA CHIMIE (FR) 2000-12-05 US disclosed
US-5847117-A Reagent and catalytic process useful for cleaving a protected functional group RHONE-POULENC CHIMIE (FR) 1998-12-08 US disclosed
US-4977272-A Radiation absorbers THE STANDARD OIL COMPANY (US) 1990-12-11 US disclosed
US-4868061-A ADDITION POLYMERS, ULTRAVIOLET RADIATION STABILIZERS THE STANDARD OIL COMPANY (US) 1989-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165393-A1 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids ADH5, ADH1C, TST ALDH1A1 231/4885CASP1 4090/4885MME 3324/4885
US-20060293536-A1 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids ADH5, ADH1C, TST ALDH1A1 154/4885CASP1 3874/4885MME 3313/4885
US-12625431-B2 EUV resist underlayer film-forming composition EEF1A1, ARF1, EMG1 ALDH1A1 2046/4885CASP1 3186/4885MME 2475/4885
US-20230391818-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION VIP, DNPEP, NPPA ALDH1A1 4623/4885CASP1 3449/4885MME 1190/4885
US-20020151744-A1 Kinetic resolutions of chiral 2-and-3-substituted carboxylic acids ADH5, ADH1C, TST ALDH1A1 218/4885CASP1 4208/4885MME 3369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.