SCHEMBL7140671

SCHEMBL7140671

O=P[PH](=O)OCC(O)CO

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2912804 0.77 LMNA (0.40) LMNAALDH1A1SMN1; SMN2KDM4EDUSP3
SCHEMBL15887085 0.75
SCHEMBL2912805 0.75
SCHEMBL27786380 0.73 LMNA (0.36) LMNAALDH1A1SMN1; SMN2KDM4EDUSP3
SCHEMBL27786849 0.73 LMNA (0.36) LMNAALDH1A1SMN1; SMN2KDM4EDUSP3
SCHEMBL27505436 0.73 LMNA (0.36) LMNAALDH1A1SMN1; SMN2KDM4EDUSP3
SCHEMBL27832027 0.73 LMNA (0.36) LMNAALDH1A1SMN1; SMN2KDM4EDUSP3
SCHEMBL27815197 0.73 LMNA (0.36) LMNAALDH1A1SMN1; SMN2KDM4EDUSP3
SCHEMBL141573 0.72
Water SCHEMBL27952503 0.71 LMNA (0.35) LMNAALDH1A1KDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6511677-B1 Oral drug delivery system; such as octadeca-2,4-dienoyl-polyethylene glycol-succinic acid with covalently bound ligand that targets intestine mucosal tissue ORASOMOL TECHNOLOGIES, INC. 2003-01-28 US disclosed
US-6500453-B2 DRUG DELIVERY ORASOMOL TECHNOLOGIES, INC. 2002-12-31 US disclosed
US-20020041861-A1 Novel polymerizable fatty acids, phospholipids and polymerized liposomes therefrom ORASOMAL TECHNOLOGIES, INC. 2002-04-11 US disclosed
US-6187335-B1 DRUGS, POLYESTERETHER COPOLYMERS AND PHOSPHOLIPIDS ORASOMAL TECHNOLOGIES, INC. 2001-02-13 US disclosed
WO-2000076476-A1 ADJUVANT-CONTAINING POLYMERIZED LIPOSOMES FOR ORAL, MUCOSAL OR INTRANASAL VACCINATION ENDOREX CORPORATION (US) 2000-12-21 WO disclosed
EP-1049759-A1 NOVEL POLYMERIZABLE FATTY ACIDS, PHOSPHOLIPIDS AND POLYMERIZED LIPOSOMES THEREFROM Orasomal Technologies, Inc. (US) 2000-11-08 EP disclosed
WO-1999033940-A1 NOVEL POLYMERIZABLE FATTY ACIDS, PHOSPHOLIPIDS AND POLYMERIZED LIPOSOMES THEREFROM ORASOMAL TECHNOLOGIES, INC. (US) 1999-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020041861-A1 Novel polymerizable fatty acids, phospholipids and polymerized liposomes therefrom SGMS1, SGMS2, PHOSPHO1 LMNA 2418/4885ALDH1A1 4723/4885SMN1; SMN2 4501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.