Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 13/20 | 0.60 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133702 | 0.90 | CTSL (0.70) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL7132876 | 0.86 | CTSL (0.65) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL7133785 | 0.83 | SIRT2 (0.66) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL7331328 | 0.80 | CTSL (0.71) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL29556789 | 0.80 | CA12 (0.57) | SIRT2SIRT1SIRT3SIRT5HDAC3 | |
| SCHEMBL22689917 | 0.80 | HDAC8 (0.56) | SIRT2SIRT1SIRT5HDAC3HDAC4 | |
| SCHEMBL7134194 | 0.79 | CTSL (0.58) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL7333974 | 0.78 | CTSL (0.69) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL4838789 | 0.78 | SIRT5 (0.76) | SIRT2SIRT1SIRT3SIRT5HDAC3 | |
| SCHEMBL7131822 | 0.78 | CTSL (0.64) | SIRT2SIRT1SIRT3CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092634-A1 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. | 2003-05-15 | — | — | US | disclosed |
| US-6506733-B1 | Which process comprises hydrogenating a compound of Formula 9: presence of a catalytic amount of 20% palladium hydroxide on carbon. | AXYS PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092634-A1 | Novel compounds and compositions as protease inhibitors | SERPINB1, HPN, CTRL | SIRT2 2674/4885SIRT1 1375/4885SIRT3 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.