Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 2/20 | 0.54 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.51 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19337065 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HSD17B10ESR1ALOX5APFEN1 | |
| SCHEMBL19337154 | 0.79 | ALDH1A1 (0.59) | PER2CRY1CRY2ALDH1A1HSD17B10 | |
| SCHEMBL1291312 | 0.78 | ALOX5AP (0.43) | PER2ALDH1A1HSD17B10ESR1ALOX5AP | |
| SCHEMBL1291148 | 0.78 | ESR1 (0.60) | ALDH1A1HSD17B10ESR1ALOX5APFEN1 | |
| SCHEMBL31689520 | 0.76 | CRY1 (0.49) | PER2CRY1CRY2ALDH1A1KMT2A | |
| SCHEMBL12330758 | 0.76 | CRY1 (0.49) | PER2CRY1CRY2ALDH1A1KMT2A | |
| SCHEMBL1291494 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HSD17B10ESR1ALOX5APFEN1 | |
| SCHEMBL7554537 | 0.74 | KMT2A (0.54) | ALDH1A1ESR1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL21048863 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HSD17B10ESR1ALOX5APFEN1 | |
| SCHEMBL13563957 | 0.74 | CRY1 (0.48) | PER2CRY1CRY2HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334087-A1 | CYCLOALKYLFLUOROSULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032858-A1 | CYCLOALKYLFLUOROSULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-04-25 | — | — | WO | disclosed |