Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 4/20 | 0.39 |
| ▸ | JAK1 | P23458 | 4/20 | 0.39 |
| ▸ | TYK2 | P29597 | 4/20 | 0.39 |
| ▸ | JAK3 | P52333 | 4/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1291494 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL21048863 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL19337102 | 0.85 | ESR1 (0.40) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL17258994 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL9822673 | 0.83 | LMNA (0.42) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL19337154 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL6896705 | 0.81 | PTGER1 (0.38) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL21048978 | 0.80 | TP53 (0.52) | ALDH1A1MEN1KMT2AHSD17B10TP53 | |
| SCHEMBL1291148 | 0.79 | ESR1 (0.60) | ALDH1A1MEN1KMT2AHSD17B10HTT | |
| SCHEMBL7140817 | 0.79 | PER2 (0.54) | ALDH1A1MEN1KMT2AHSD17B10ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885344-A2 | PYRIMIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | InventisBio Co., Ltd. (CN) | 2021-09-29 | — | — | EP | disclosed |
| EP-3216786-A1 | PYRIMIDINE OR PYRIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | Shanghai Shaletech Technology Co., Ltd. (CN) | 2017-09-13 | — | — | EP | disclosed |