Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561988 | 0.81 | MAPT (0.40) | KDM4ETDP1MAPTGSK3BPOLB | |
| SCHEMBL7615932 | 0.79 | MAPT (0.39) | KDM4ETDP1MAPTGSK3B | |
| SCHEMBL7558781 | 0.79 | MAPT (0.40) | KDM4ETDP1MAPTGSK3BHSD17B1 | |
| SCHEMBL7562731 | 0.78 | HDAC4 (0.50) | KDM4EMAPTMMP1MMP12MAP3K5 | |
| SCHEMBL7617548 | 0.78 | MAPT (0.38) | KDM4ETDP1MAPTGSK3B | |
| SCHEMBL7563319 | 0.77 | HTR1A (0.36) | KDM4EMAPTGSK3BHSD17B1HSD17B2 | |
| SCHEMBL11983221 | 0.76 | SERPINE1 (0.47) | KDM4ETDP1KMT2A | |
| SCHEMBL7556667 | 0.74 | HSD17B1 (0.34) | KDM4EMAPTGSK3BKMT2AHSD17B1 | |
| SCHEMBL7563264 | 0.73 | MAPT (0.38) | KDM4ETDP1MAPTAPLNRKMT2A | |
| SCHEMBL11983220 | 0.72 | HDAC4 (0.51) | KDM4ETDP1MAPTAPLNRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095021-B1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2003-09-17 | — | — | EP | claimed |