Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558781 | 0.82 | MAPT (0.40) | MAPTHSD17B1HSD17B2KDM4EGPBAR1 | |
| SCHEMBL7558487 | 0.78 | MAPT (0.41) | MAPTHSD17B1HSD17B2KDM4EHSD17B10 | |
| SCHEMBL7563319 | 0.78 | HTR1A (0.36) | MAPTHSD17B1HSD17B2KDM4EGPBAR1 | |
| SCHEMBL7559757 | 0.76 | MAPT (0.39) | MAPTHSD17B1HSD17B2MEN1KMT2A | |
| SCHEMBL7556667 | 0.76 | HSD17B1 (0.34) | MAPTHSD17B1HSD17B2KDM4EMEN1 | |
| SCHEMBL14335694 | 0.75 | CYP19A1 (0.42) | MAPTKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL7559768 | 0.74 | MAPT (0.48) | MAPTHSD17B1HSD17B2KDM4EGPBAR1 | |
| SCHEMBL14335867 | 0.74 | USP2 (0.44) | MAPTKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL5163897 | 0.73 | HDAC4 (0.64) | MAPTTP53THRBKDM4EALDH1A1 | |
| SCHEMBL7140931 | 0.73 | KDM4E (0.36) | MAPTHSD17B1HSD17B2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224172-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | Active Biotech AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030758-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2001-05-03 | — | — | WO | disclosed |