Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398851 | 0.88 | KDM4E (0.51) | KDM4EHPGDALDH1A1PPARGHTT | |
| SCHEMBL3039556 | 0.84 | KDM4E (0.55) | KDM4EHPGDALDH1A1HTTGAA | |
| Hydrochloric Acid SCHEMBL3046433 | 0.83 | KDM4E (0.53) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL19437117 | 0.83 | RIPK1 (0.49) | KDM4EHPGDALDH1A1KMT2ALMNA | |
| SCHEMBL6325943 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HTTKMT2ALMNAPOLB | |
| SCHEMBL6136600 | 0.81 | POLB (0.50) | HPGDALDH1A1PPARGKMT2APOLB | |
| SCHEMBL2249746 | 0.81 | KDM4E (0.48) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL7139605 | 0.80 | KDM4E (0.60) | KDM4EHPGDALDH1A1PPARGHTT | |
| SCHEMBL6239035 | 0.80 | KDM4E (0.60) | KDM4EHPGDALDH1A1PPARGHTT | |
| SCHEMBL7144643 | 0.80 | KDM4E (0.60) | KDM4EHPGDALDH1A1PPARGHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098871-B1 | alpha-AMINO ACID PHENYL ESTER DERIVATIVES | AKZO NOBEL NV (NL) | 2003-07-09 | — | — | EP | disclosed |
| US-6451854-B1 | α-amino acid phenyl ester derivatives | AKZO NOBEL N.V. (NL) | 2002-09-17 | — | — | US | disclosed |