Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 6/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 6/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563004 | 0.81 | ALDH1A1 (0.44) | ALDH1A1PIK3C2BPIK3CDPIK3CGMTOR | |
| SCHEMBL827977 | 0.73 | ALDH1A1 (0.47) | ALDH1A1ABCC1MEN1MAPTKMT2A | |
| SCHEMBL828076 | 0.71 | ALDH1A1 (0.48) | ALDH1A1MAPTMAPK9MAPK10 | |
| SCHEMBL22362588 | 0.68 | ALDH1A1 (0.44) | ALDH1A1MAPTMAPK9MAPK10 | |
| SCHEMBL17979907 | 0.66 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27883229 | 0.66 | MAPT (0.46) | ALDH1A1PIK3C2BMEN1MAPTKMT2A | |
| SCHEMBL827916 | 0.64 | ALDH1A1 (0.48) | ALDH1A1PIK3C2BPIK3CDPIK3CGMTOR | |
| SCHEMBL533138 | 0.64 | NPC1 (0.46) | ALDH1A1CNR2MEN1NPC1MAPT | |
| SCHEMBL1200132 | 0.64 | MAPK1 (0.41) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL14984899 | 0.64 | CNR2 (0.53) | CNR2CNR1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351946-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002020500-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |