Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141105 | 0.81 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MAPTMAPK9MAPK10 | |
| SCHEMBL6073272 | 0.70 | MAPT (0.47) | ALDH1A1NPSR1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL28516755 | 0.70 | RAB9A (0.45) | ALDH1A1NPSR1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL30798758 | 0.70 | HPGD (0.45) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL11527987 | 0.69 | ALDH1A1 (0.67) | ALDH1A1NPSR1KDM4EPOLBALOX12 | |
| SCHEMBL4996506 | 0.69 | ALDH1A1 (0.63) | ALDH1A1NPSR1KDM4EPOLBALOX12 | |
| SCHEMBL7089470 | 0.69 | KDM4E (0.45) | ALDH1A1KDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL14271380 | 0.67 | KCNQ2 (0.53) | ALDH1A1NPSR1SMN1; SMN2LMNAGAA | |
| SCHEMBL827916 | 0.67 | ALDH1A1 (0.48) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL4945050 | 0.67 | KCNQ2 (0.55) | ALDH1A1NPSR1SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020165218-A1 | Materials and methods to potentiate cancer treatment | LUITPOLD PHARMACEUTICALS, INC. | 2002-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165218-A1 | Materials and methods to potentiate cancer treatment | DCK, CHEK2, CHEK1 | ALDH1A1 3519/4885NPSR1 4453/4885KDM4E 2518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.