Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136440 | 0.87 | RARB (0.50) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL7136782 | 0.86 | RARB (0.52) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL5962074 | 0.84 | TSHR (0.59) | NR5A1TSHRLTA4HPLA2G4BALOX5 | |
| SCHEMBL7054030 | 0.81 | PTGS2 (0.57) | RARBTSHRPTPN11PLA2G4BPTGES | |
| SCHEMBL9252719 | 0.80 | NR5A1 (0.59) | RARBNR5A1TSHRLTA4HPLA2G4B | |
| SCHEMBL7786342 | 0.80 | RARB (0.54) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL8396365 | 0.80 | TSHR (0.58) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL7789296 | 0.80 | RARB (0.54) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL2779495 | 0.78 | LTA4H (0.70) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL9153955 | 0.78 | LTA4H (0.70) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509507-B2 | Reacting a 6-membered aromatic ring with 1,4- position ester or benzylic OH groups with a second aromatic in a palladium catalyzed cross-coupling; electroluminescence | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2003-01-21 | — | — | US | disclosed |
| US-20020087030-A1 | Polymerizable biaryls, process for their preparation and their use | MERCK PATENT GMBH (DE) | 2002-07-04 | — | — | US | disclosed |
| US-6323373-B1 | USED TO OBTAIN POLYMERS WHICH ARE USED AS ELECTROLUMINESCENCE MATERIALS | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020087030-A1 | Polymerizable biaryls, process for their preparation and their use | PAH, TYR, PAICS | RARB 1893/4885CYP3A4 14/4885CYP2D6 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.